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She later parted ways with her publicist at the time, who had not informed her in advance."There were a lot of cooks in the kitchen, a lot of voices around me, and I wanted to step away so I could hear my own voice again", Mc Adams said in 2013.In 2005, she starred in the romantic comedy Wedding Crashers, the psychological thriller Red Eye, and the comedy-drama The Family Stone.
Watch the poignancy of the scene when she meets her boyfriend's family." In 2009, Mc Adams starred with Russell Crowe, Helen Mirren and Ben Affleck in the political thriller State of Play, based on the BBC drama television series of the same name.
In 2010, Mc Adams appeared in her first star vehicle, the comedy Morning Glory.
In 2015, her highest profile roles were in the second season of the HBO crime drama True Detective, and as journalist Sacha Pfeiffer in the drama Spotlight.
Mc Adams' break-out role came in 2004, when she starred in the comedy film Mean Girls opposite Lindsay Lohan, Lacey Chabert and Amanda Seyfried, based on Rosalind Wiseman's book Queen Bees and Wannabes.
Mc Adams was 25 years old when she was cast as the mean high school queen bee Regina George, and she modelled her character on Alec Baldwin's performance in the drama Glengarry Glen Ross (1992).while Roger Ebert of the Chicago Sun-Times asserted that "she brings more presence and credibility to her role than is really expected; she acts without betraying the slightest awareness that she's inside a genre.